Cutaneous T-Cell Lymphoma - Summary, Symptoms & Treatments

What is cutaneous T-cell lymphoma?

Cutaneous T-cell lymphoma is a rare cancer and one of several types of cancer known as non-Hodgkin lymphoma.  Cutaneous T-cell lymphoma starts in the white blood cells, called T cells, which help the body’s immune system fight off germs. When abnormalities develop these cells begin to attack the skin, however, it is not skin cancer. There are several types of cutaneous T-cell lymphoma; some grow slowly and others are more aggressive. Mycosis fungoides is the most common type.
Back to Top

What are the signs and symptoms of cutaneous T-cell lymphoma?

Skin changes are the most common signs of cutaneous T-cell lymphoma, including:

• Skin rashes that are red or discolored
• Raised bumps or patches on the skin that are dry, itchy or scaly

These can grow in size and begin to cover more of the skin surface. Over time, they may thicken and cause tumors on the skin. It is important to contact your primary health care provider if you experience any of these on a persistent basis.
Back to Top

How is cutaneous T-cell lymphoma diagnosed?

Diagnosing cutaneous T-cell lymphoma begins with a physical examination so that your doctor can evaluate the symptoms you are experiencing. Additional information to confirm a diagnosis can be obtained through:

• Blood tests to assess the type and extent of the lymphoma
• Imaging tests, such as CT or PET scans, to see if the cancer has spread to the lymph nodes or other organs
• Biopsy to remove small pieces of tissue from the skin that are viewed under a microscope to check for cancer cells

Back to Top

What causes cutaneous T-cell lymphoma?

The exact cause cutaneous T-cell lymphoma is not known.
Back to Top

What are common risk factors for cutaneous T-cell lymphoma?

While cutaneous T-cell lymphoma can occur at any age, the risk increases with age. The majority of cases are diagnosed in adults between age 50 and 60. Cutaneous T-cell lymphoma is more common in males than in females. Researchers have found that individuals with a weakened immune system caused by certain infections or viruses may be more likely to develop cutaneous T-cell lymphoma.
Back to Top

Is cutaneous T-cell lymphoma genetic?

Multiple genetic factors that are inherited from our parents do increase the risk for some cancers and may contribute to an increase in the risk for cutaneous T-cell lymphoma. It is best to talk with your doctor regarding any genetic predisposition to this form of cancer.
Back to Top

Is cutaneous T-cell lymphoma curable?

There is no cure for cutaneous T-cell lymphoma, but it is highly treatable. Most cases are diagnosed at early stages, before the cancer has spread to lymph nodes or other organs, and patients are able to live symptom-free for many years.
Back to Top

How is cutaneous T-cell lymphoma treated?

Each patient and each cancer is unique. At FCS, physicians develop a personalized treatment plan in partnership with patients based on the type and stage of the cancer and whether it has spread to other parts of the body. There are many treatment options for cutaneous T-cell lymphoma. These include creams and ointments that can be applied directly to the skin and light therapy (phototherapy) that exposes the skin to various types of ultraviolet rays, as well as targeted therapy medicines, chemotherapy or radiation to attack and kill cancer cells. Through our extensive clinical trials research program, FCS offers our patients access to the most advanced treatment options available. FCS is at the forefront of developing novel therapies that are proving effective and considered best-in-class treatments for many forms of cancer.
Back to Top